Symbol
Name
ID

Ptgs2
prostaglandin-endoperoxide synthase 2
MGI:97798

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Abnormal reproductive system morphology	Prostate cancer	Absent vas deferens	Ovarian carcinoma	Male infertility
Disease(s) Associated with PTGS2	Abnormal reproductive system morphology	Prostate cancer	Absent vas deferens	Ovarian carcinoma	Male infertility
cystic fibrosis
pancreatic cancer
prostate cancer
sarcoidosis

Mouse Phenotypes

reproductive system phenotype

abnormal primary polar body morphology

impaired granulosa cell differentiation

abnormal decidualization

abnormal corpus luteum morphology

absent corpus luteum

abnormal cumulus expansion

small ovary

abnormal reproductive system physiology

decreased superovulation rate

failure of superovulation

decreased ovulation rate

failure of embryo implantation

female infertility

reduced female fertility

decreased litter size

impaired fertilization

Availability

Mouse Genotype

Ptgs2^tm1.1Fun/Ptgs2^tm1.1Fun

Ptgs2^tm1.1Wls/Ptgs2^tm1.1Wls

Ptgs2^tm1Jed/Ptgs2^tm1Jed

Ptgs2^tm1Unc/Ptgs2^tm1Unc

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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